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Allergology · Skin allergies

Reactions to metals (nickel, chromium…)

Reactions to metals (nickel, chromium, cobalt) most often take the form of allergic contact eczema, caused by delayed hypersensitivity. Patch tests identify the metal responsible so that everyday prevention can be adapted.

Written by Dr A. Turcarelli, dermatologist and allergist Updated 5 January 2026 5 min read

Réactions aux métaux (nickel, chrome…)

Introduction

Nickel is the most common cause, followed by chromium and cobalt. The lesions appear after repeated or prolonged contact with everyday metal objects or in a work setting.

Symptoms

  • Well-defined redness at the point of contact
  • Intense itching
  • Eczematous patches, small blisters
  • Weeping and crusting in the acute phase
  • Thickening and cracks in the chronic phase
  • Common sites: hands, wrists, earlobes, neck, abdomen (buckles, belts)

Causes

Nickel
jewellery, watches, buttons, zips, phones
Chromium
cement, leather, industrial products
Cobalt
metal alloys, tools
Prolonged or repeated exposure
Often work-related (construction, industry, hairdressing)

Diagnosis

  1. Targeted history (items worn, occupation)
  2. Skin examination
  3. Patch tests including metals
  4. Reading at 48–72 hours
  5. Precise identification of the metal responsible

Treatments

Strict avoidance of the allergenic metal
Replacement with hypoallergenic materials
Topical corticosteroids during flare-ups
Emollients to repair the skin barrier
Workplace adjustments if needed

Management

Identify the metal responsible

Prevent the lesions from becoming chronic

Avoid recurrences

Improve your quality of life in the long term

Frequently asked questions

Consultation for reactions to metals (nickel, chromium…)

Consultation with a confirmed diagnosis and a written treatment plan.

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