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Dermatology · Viral skin infections

Genital herpes

Genital herpes is a common sexually transmitted infection caused by herpes simplex virus type 2 (HSV-2) and, increasingly, by HSV-1. It causes outbreaks of small, painful blisters that turn into sores on the genital, perigenital or anal area. After the first infection, the virus remains dormant in the nerve ganglia and can reactivate from time to time. It can be transmitted even when there are no symptoms. Effective antiviral treatments relieve outbreaks and reduce how often they occur.

Written by Dr A. Turcarelli, dermatologist and allergist Updated 4 January 2026 6 min read

Herpès génital

Introduction

Genital herpes is a chronic viral infection caused mainly by herpes simplex virus type 2 (HSV-2) and, less often, by HSV-1. It is characterised by recurrent flare-ups of painful blistering lesions in the genital or perigenital area. After the initial infection, the virus remains dormant in the body and can reactivate from time to time.

Symptoms

  • Clusters of blisters on a red base
  • Painful ulcers after the blisters burst
  • Local burning, tingling or itching
  • Pain on passing urine
  • Discomfort during sexual intercourse
  • Possible swollen lymph nodes in the groin
  • Fever and general malaise during the initial infection
  • Recurrent episodes of varying severity

Causes

Infection with herpes simplex virus (HSV-2 or HSV-1)
Transmission through skin and mucosal contact, usually sexual
Transmission possible even when no lesions are visible
Triggers for recurrences
stress fatigue fever weakened immune system
stress
fatigue
fever
weakened immune system

Diagnosis

  1. Clinical diagnosis in most cases
  2. Viral swab (PCR) from a recent lesion if needed
  3. Blood tests (serology) useful in certain situations (initial infection, testing for couples)
  4. Differential diagnosis with: other STIs aphthous ulcers inflammatory skin conditions
  5. other STIs
  6. aphthous ulcers
  7. inflammatory skin conditions

Treatments

Aciclovir
Valaciclovir
Famciclovir
Treatment of flare-ups
Long-term suppressive treatment for frequent recurrences
Painkillers if needed
Appropriate local hygiene
Avoiding sexual intercourse during flare-ups
No specific device-based treatment
Specialist medical care and patient education

Management

Dermatological or venereological care

Clear information on the chronic nature of the infection

Psychological support if the emotional impact is significant

Advice for the partner or partners

Regular follow-up in the event of frequent recurrences

Frequently asked questions

Consultation for genital herpes

Consultation with a confirmed diagnosis and a written treatment plan.

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