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Allergology · Food allergies

Oral allergy syndrome

Oral allergy syndrome (OAS), also known as pollen-food syndrome, is a cross-reactive allergy that affects people already sensitised to pollen. It causes itching or tingling of the lips, mouth and throat within minutes of eating certain raw fruits, vegetables or nuts whose proteins resemble those of pollen. Symptoms are usually mild and often disappear when the food is cooked.

Written by Dr A. Turcarelli, dermatologist and allergist Updated 5 January 2026 5 min read

Introduction

Symptoms are usually local and immediate.

Symptoms

  • Tingling or itching in the mouth
  • Burning sensation on the lips, tongue or palate
  • Mild swelling of the lips, tongue or throat
  • Itchy throat
  • Rarely: difficulty swallowing

Causes

Pollen sensitisation (birch, grasses, ragweed…)
Cross-reaction between pollens and raw foods
Heat-labile proteins (destroyed by cooking)
Atopic background (allergic rhinitis, asthma, eczema)
Apple, pear, peach, apricot, cherry
Kiwi, banana
Carrot, celery
Hazelnut, almond
Raw tomato

Diagnosis

  1. Detailed history (known pollen allergies, trigger foods)
  2. Immediate timing of symptoms
  3. Skin prick tests with pollens and raw foods
  4. Specific IgE testing if needed

Treatments

Targeted avoidance of the culprit foods when raw
Cooked or peeled foods can often be eaten
Antihistamines if symptoms are bothersome
Treatment of associated allergic rhinitis
Adrenaline prescribed only in rare severe cases
when raw

Management

Identify cross-reactions precisely

Reassure patients that the condition is often benign

Avoid unnecessary food restrictions

Adjust the seasonal management of respiratory allergies

Frequently asked questions

Consultation for oral allergy syndrome

Consultation with a confirmed diagnosis and a written treatment plan.

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