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Dermatology · Viral skin infections

Roseola infantum

Roseola infantum, or exanthem subitum, is a common, benign viral infection of infants and young children, especially between 6 months and 2 years of age. It is mainly caused by human herpesvirus 6 (HHV-6) and, more rarely, HHV-7. It causes a high fever lasting about three days, followed by a pink rash just as the fever subsides.

Written by Dr A. Turcarelli, dermatologist and allergist Updated 4 January 2026 6 min read

Roséole infantile

Introduction

It is characterised by a sudden high fever followed, once the fever has gone, by a temporary skin rash. It usually resolves on its own.

Symptoms

  • Sudden high fever (often > 39 °C) lasting 3 to 5 days
  • Child generally remains relatively well despite the fever
  • Fever drops suddenly
  • A pink maculopapular rash then appears
  • Rash mainly on the trunk, then the neck and limbs
  • Lesions are not itchy
  • Possible irritability
  • Possible febrile seizures (rare)

Causes

Infection with HHV-6 (mainly) or HHV-7
Spread through respiratory droplets or saliva
Very common infection before the age of 2
Incubation period
5 to 15 days
Contagious mainly during the feverish phase

Diagnosis

  1. Diagnosis is essentially clinical
  2. Typical pattern: high fever followed by a rash as the fever falls
  3. No further tests needed routinely
  4. Serology or PCR reserved for atypical situations
  5. Differential diagnosis with: Measles Rubella Other viral rashes
  6. Measles
  7. Rubella
  8. Other viral rashes

Treatments

Fever-reducing medicines suited to the child’s age
Adequate fluid intake
Clinical monitoring
Rest
Temperature monitoring
Information and reassurance for parents
No specific dermatological technology indicated
Simple clinical follow-up

Management

Paediatric or dermatological care

Monitoring of infants at risk of febrile seizures

Clear information on the benign course

No strict isolation needed once the fever has gone

Frequently asked questions

Consultation for roseola infantum

Consultation with a confirmed diagnosis and a written treatment plan.

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